| Primary Identifier | MGI:1353479 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 30805 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carnitine transmembrane transporter activity. Acts upstream of or within carnitine metabolic process; carnitine transport; and triglyceride metabolic process. Located in apical plasma membrane and mitochondrial membrane. Is expressed in several structures, including integumental system; liver; musculoskeletal system; nervous system; and nose. Used to study inflammatory bowel disease 1. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human SLC22A4 (solute carrier family 22 member 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete loss of ergothioneine with reduced absorption and increased excretion and increased susceptibility of small intestine to inflammation following ischemia and reperfusion. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
