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Protein Coding Gene : Acsl6 acyl-CoA synthetase long-chain family member 6
Primary Identifier  MGI:894291 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  216739
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables long-chain fatty acid-CoA ligase activity. Acts upstream of or within neuroblast proliferation. Located in mitochondrion. Is expressed in heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia and leukemia. Orthologous to human ACSL6 (acyl-CoA synthetase long chain family member 6).
PHENOTYPE: Knockout mice show altered or impaired lipogenesis and amino acid and nucleotide metabolism in the brain as well as changes to coordination and startle reflex. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW050338,
  • MGI:2444956,
  • fatty acid Coenzyme A ligase, long chain 6,
  • Acsl6,
  • Facl6,
  • long-chain acyl-CoA synthetase-like,
  • Lacsl,
  • RIKEN cDNA A330035H04 gene,
  • AW050338,
  • acyl-CoA synthetase long-chain family member 6,
  • A330035H04Rik,
  • MGI:2144490
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1 Involved In Mutations

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