| Primary Identifier | MGI:2384761 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 192786 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; microvillus assembly; and positive regulation of GTPase activity. Predicted to be located in centrosome and cytosol. Predicted to be active in apical plasma membrane and endocytic vesicle. Is expressed in nervous system. Orthologous to human RAPGEF6 (Rap guanine nucleotide exchange factor 6). PHENOTYPE: Mice homozygous for a null allele exhibit an inlarged spleen, increased IgE and IgG levels and altered cytokine production. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
