| Primary Identifier | MGI:1321133 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 15254 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables deSUMOylase activity. Involved in positive regulation of calcium-mediated signaling and protein desumoylation. Located in nucleus. Is expressed in several structures, including genitourinary system; gut; mammary gland; nervous system; and spleen. Human ortholog(s) of this gene implicated in Gamstorp-Wohlfart syndrome. Orthologous to human HINT1 (histidine triad nucleotide binding protein 1). PHENOTYPE: Homozygous mutant animals do not exhibit an overt phenotype, though one line of mutant mice was shown to be more susceptible to carcinogen-induced tumors than wild-type. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
