Primary Identifier | MGI:2441765 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 216749 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neuropeptide receptor activity. Acts upstream of or within several processes, including grooming behavior; neuropeptide signaling pathway; and reduction of food intake in response to dietary excess. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human NMUR2 (neuromedin U receptor 2). PHENOTYPE: Mice homozygous for one knock-out allele exhibit increased chemical and thermal nociception thresholds, insensitivity to treatment with Nmu or Nms, and altered weight gain following a fast or when fed a high-fat diet that can be sex-dependent. [provided by MGI curators] |