Primary Identifier | MGI:1333794 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 216767 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including brain; cardiovascular system; early conceptus; genitourinary system; and gut. Orthologous to human MRPL22 (mitochondrial ribosomal protein L22). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, abnormal mitochondrial morphology and physiology, and complete lethality prior to organogenesis. [provided by MGI curators] |