| Primary Identifier | MGI:1917413 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 70163 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in defense response to Gram-negative bacterium. Located in extracellular space. Is expressed in midgut. Orthologous to human LYPD8 (LY6/PLAUR domain containing 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit invasion of the colonic epithelia by intestinal flagellated bacteria and increased susceptibility to DSS-induced colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
