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Protein Coding Gene : Trim58 tripartite motif-containing 58
Primary Identifier  MGI:2684862 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  216781
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytoplasm. Orthologous to human TRIM58 (tripartite motif containing 58).
PHENOTYPE: Homozygous null mice exhibit no overt phenotype but show delayed resolution of DSS-induced colitis. [provided by MGI curators]
  • synonyms:
  • gene model 16, (NCBI),
  • tripartite motif-containing 58,
  • Gm16,
  • Trim58,
  • Gm1783,
  • LOC216781,
  • MGI:2686629,
  • LOC386443,
  • gene model 1783, (NCBI)
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