Primary Identifier | MGI:1352758 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 29869 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein serine/threonine kinase activity. Involved in autophagy and response to starvation. Acts upstream of or within several processes, including axonogenesis; negative regulation of collateral sprouting; and somatic sensory system development. Located in phagophore assembly site membrane. Is expressed in facial bone primordium; nervous system; and sensory organ. Orthologous to human ULK2 (unc-51 like autophagy activating kinase 2). PHENOTYPE: Homozygous mutation of this gene results in an increased anxiety-like response in males. [provided by MGI curators] |