| Primary Identifier | MGI:1890218 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 56697 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein kinase A binding activity. Acts upstream of or within protein localization. Located in mitochondrion. Is expressed in several structures, including central nervous system; eye; genitourinary system; pancreas; and skin. Orthologous to human AKAP10 (A-kinase anchoring protein 10). PHENOTYPE: Mice homozygous for a gene trapped allele display sinus arrhythmia, sinus pauses, and atrioventricular heart block indicating excessive vagus nerve sensitivity; about 50% of homozygous and 25% of heterozygous mutant mice die in the first year of life, and survival is sensitive to genetic background. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
