Primary Identifier | MGI:1920389 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 73139 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable carbon-sulfur lyase activity and metal ion binding activity. Predicted to be involved in several processes, including centromere complex assembly; pericentric heterochromatin formation; and positive regulation of cytokinesis. Predicted to act upstream of or within ameboidal-type cell migration. Predicted to be located in several cellular components, including microtubule cytoskeleton; midbody; and nucleus. Predicted to be active in kinetochore; nucleus; and spindle midzone. Orthologous to several human genes including CENPV (centromere protein V). PHENOTYPE: Mice homozygous for a null allele exhibit reduced female fertility associated with abnormal female meiosis and meitotic spindle integrity. [provided by MGI curators] |