Primary Identifier | MGI:1339711 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 17879 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction. Located in A band and intercalated disc. Is expressed in several structures, including gonad; gut; hemolymphoid system gland; integumental system; and skeletal musculature. Orthologous to human MYH1 (myosin heavy chain 1). PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced growth, muscular weakness, kyphosis, and abnormal kinetics of muscle contraction and relaxation. [provided by MGI curators] |