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Protein Coding Gene : Stx8 syntaxin 8
Primary Identifier  MGI:1890156 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  55943
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ubiquitin protein ligase binding activity. Acts upstream of or within cellular response to type II interferon. Located in phagocytic vesicle. Is active in late endosome. Orthologous to human STX8 (syntaxin 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit defects in platelet dense granule secretion, aggregation, and thrombus stability. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 4930571E13 gene,
  • Stx8,
  • MGI:1915004,
  • 4930571E13Rik,
  • MGI:1915791,
  • 1110002H11Rik,
  • MGI:1925545,
  • 0610007H08Rik,
  • RIKEN cDNA 0610007H08 gene,
  • RIKEN cDNA 1110002H11 gene,
  • syntaxin 8
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