Primary Identifier | MGI:1098283 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 18626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity; DNA-binding transcription factor binding activity; and kinase binding activity. Involved in several processes, including entrainment of circadian clock by photoperiod; negative regulation of glucocorticoid receptor signaling pathway; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; heart; nervous system; and thymus. Used to study attention deficit hyperactivity disorder. Orthologous to human PER1 (period circadian regulator 1). PHENOTYPE: Homozygous null mice display a persistent circadian rhythm, but they have a shorter period and their ability to maintain the precision and the stability of the period is impaired. [provided by MGI curators] |