| Primary Identifier | MGI:1098228 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11688 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables arachidonate 15-lipoxygenase activity; arachidonate 8(S)-lipoxygenase activity; and linoleate 9S-lipoxygenase activity. Involved in several processes, including fatty acid metabolic process; positive regulation of keratinocyte differentiation; and positive regulation of peroxisome proliferator activated receptor signaling pathway. Predicted to be located in several cellular components, including adherens junction; cytosol; and focal adhesion. Orthologous to human ALOX15B (arachidonate 15-lipoxygenase type B). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired recovery from influenza infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
