| Primary Identifier | MGI:88109 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11932 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATPase binding activity; P-type sodium:potassium-exchanging transporter activity; and protein heterodimerization activity. Involved in cell-substrate adhesion; negative regulation of glial cell migration; and positive regulation of neuron projection development. Acts upstream of or within several processes, including brain development; motor behavior; and photoreceptor cell maintenance. Located in several cellular components, including astrocyte end-foot; cell body membrane; and external side of plasma membrane. Is expressed in several structures, including brain; early conceptus; genitourinary system; retina; and spinal cord. Orthologous to human ATP1B2 (ATPase Na+/K+ transporting subunit beta 2). PHENOTYPE: Homozygotes for a null mutation exhibit lack of motor coordination, tremors, limb paralysis, enlarged ventricles, photoreceptor degeneration, vacuoles adjoining capillaries of brain stem, thalamus, striatum, and spinal cord, and death at 17-18 days of age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
