Primary Identifier | MGI:1916833 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 69583 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable receptor ligand activity. Acts upstream of or within immunoglobulin mediated immune response; positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; and positive regulation of cell population proliferation. Located in external side of plasma membrane. Is expressed in future midbrain; nervous system; renal vasculature; retina outer nuclear layer; and spleen. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human TNFSF13 (TNF superfamily member 13). PHENOTYPE: Homozygous null mice are viable and fertile. No apparent defects of the immune system have been reported. [provided by MGI curators] |