Primary Identifier | MGI:2681835 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 216856 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cell adhesion molecule binding activity; identical protein binding activity; and neurexin family protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission; regulation of signal transduction; and synapse organization. Acts upstream of or within several processes, including protein localization to cell surface; regulation of respiratory gaseous exchange by nervous system process; and synapse organization. Located in synapse. Is active in several cellular components, including dopaminergic synapse; glycinergic synapse; and postsynaptic specialization membrane. Is expressed in brain; brainstem; cerebral cortex; and hippocampus. Used to study schizophrenia. Orthologous to human NLGN2 (neuroligin 2). PHENOTYPE: Mice homozygous for a conditional ready allele are viable and fertile. [provided by MGI curators] |