Primary Identifier | MGI:106248 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 276770 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable U6 snRNA binding activity and translation elongation factor activity. Acts upstream of or within positive regulation of apoptotic process. Located in cytoplasm and nucleus. Is active in synapse. Is expressed in several structures, including central nervous system; extraembryonic component; eye; liver; and pancreas epithelium. Orthologous to several human genes including EIF5A (eukaryotic translation initiation factor 5A). PHENOTYPE: Mice homozygous for a gene trap allele display lethality prior to somite formation and reduced blastocyst cell proliferation. [provided by MGI curators] |