| Primary Identifier | MGI:1096372 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 53422 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including chromatin binding activity; mRNA 3'-UTR binding activity; and ribonucleoprotein complex binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within germ cell development and post-transcriptional regulation of gene expression. Located in cytoplasm. Part of ribonucleoprotein complex. Is expressed in several structures, including eye; gonad; lung; trunk somite; and uterus. Orthologous to human YBX2 (Y-box binding protein 2). PHENOTYPE: Homozygous disruption of this gene leads to both male and female infertility. Spermatogenesis terminates in postmeiotic germ cells with no sperm seen in the epididymis and a marked increase of apoptosis during meiosis. Adult females exhibit a few growingfollicles and no corpora lutea. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
