| Primary Identifier | MGI:1914431 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 67181 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase activity. Acts upstream of or within gamete generation; mesoderm development; and positive regulation of canonical Wnt signaling pathway. Located in cytoplasm and nucleus. Is expressed in limb mesenchyme and skeleton. Orthologous to human CTDNEP1 (CTD nuclear envelope phosphatase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality, abnormal extraembryonic tissue development, poorly developed head fold and trunk and severely reduced primordial germ cell numbers due to a failure to transit to mesoderm. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
