| Primary Identifier | MGI:88082 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 11890 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable D-mannose binding activity and fucose binding activity. Acts upstream of or within glycoprotein metabolic process; lipid homeostasis; and regulation of protein stability. Predicted to be located in endoplasmic reticulum quality control compartment and perinuclear region of cytoplasm. Predicted to be active in external side of plasma membrane. Is expressed in embryo. Orthologous to human ASGR2 (asialoglycoprotein receptor 2). PHENOTYPE: Homozygous mutation of this gene results in reduced ASGR1 protein expression and deficiency in clearance of asialoorsomucoid. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
