| Primary Identifier | MGI:96975 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 17312 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable D-mannose binding activity; fucose binding activity; and pattern recognition receptor activity. Acts upstream of or within connective tissue replacement involved in inflammatory response wound healing. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; hemolymphoid system gland; and liver. Orthologous to human CLEC10A (C-type lectin domain containing 10A). PHENOTYPE: Homozygotes for a targeted null mutation exhibit elevated red blood cell counts but appear to be otherwise normal. Homozygosity for the p.Q236* mutation affects cell surface expression and leads to hypersensitivity to house dust mites. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
