Primary Identifier | MGI:3603821 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 574428 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone deacetylase binding activity. Acts upstream of or within negative regulation of DNA-templated transcription and spermatid development. Located in cytoplasm and male germ cell nucleus. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in spermatogenic failure 14. Orthologous to human ZMYND15 (zinc finger MYND-type containing 15). PHENOTYPE: Mice homozygous for a knock-out allele of Cxcl16 and Zmynd15 exhibit abnormal spermiogenesis and reduced male fertility. [provided by MGI curators] |