Primary Identifier | MGI:2135957 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 216874 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in several structures, including brain; eye; foregut; male reproductive gland or organ; and urinary system. Orthologous to human CAMTA2 (calmodulin binding transcription activator 2). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and free of obvious cardiac defects, but show reduced pathophysiologic cardiac hypertrophy in response to diverse stress stimuli. [provided by MGI curators] |