Primary Identifier | MGI:3610314 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 327957 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables molecular adaptor activity. Involved in several processes, including pattern recognition receptor signaling pathway; positive regulation of cytokine production; and positive regulation of signal transduction. Located in phagocytic vesicle. Part of receptor complex. Colocalizes with filopodium and ruffle. Orthologous to human SCIMP (SLP adaptor and CSK interacting membrane protein). PHENOTYPE: Homozygous mutant mice are anemic. Male mutants also exhibit increased mean body weight and an increased mean serum cholesterol level. [provided by MGI curators] |