Primary Identifier | MGI:106181 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 18432 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables E-box binding activity and transcription corepressor activity. Involved in circadian regulation of gene expression and negative regulation of DNA-templated transcription. Acts upstream of or within respiratory electron transport chain. Located in cytoplasm and nucleolus. Part of NLS-dependent protein nuclear import complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb. Orthologous to human MYBBP1A (MYB binding protein 1a). PHENOTYPE: Mice homozygous for a targeted allele exhibit embryonic lethality before blastocyst formation. [provided by MGI curators] |