| Primary Identifier | MGI:1194503 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 53313 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including calcium-dependent ATPase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and transmembrane transporter binding activity. Predicted to be involved in several processes, including calcium ion transport from cytosol to endoplasmic reticulum; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and positive regulation of cysteine-type endopeptidase activity. Located in endoplasmic reticulum. Is expressed in diaphragm. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). PHENOTYPE: Homozygous mutation of this gene results in reduced endothelial-dependent relaxation in the aorta. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
