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Protein Coding Gene : Shpk sedoheptulokinase
Primary Identifier  MGI:1921887 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  74637
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables sedoheptulokinase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and pentose-phosphate shunt, non-oxidative branch. Located in cytoplasm. Is expressed in trigeminal ganglion. Orthologous to human SHPK (sedoheptulokinase).
PHENOTYPE: Homozygous null mice show pentose phosphate pathway dysregulation in the liver and an increase in urinary sedoheptulose and erythritol levels. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW260459,
  • Shpk,
  • sedoheptulokinase,
  • Carkl,
  • MGI:2144081,
  • AI194947,
  • carbohydrate kinase-like,
  • AW260459,
  • expressed sequence AI194947,
  • RIKEN cDNA 4930431K22 gene,
  • 4930431K22Rik,
  • MGI:2144522
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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

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