Primary Identifier | MGI:1921398 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 74148 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity. Predicted to be involved in intracellular distribution of mitochondria and mitochondrion organization. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; musculature; and naris. Orthologous to human CLUH (clustered mitochondria homolog). PHENOTYPE: Constitutive homozygous KO affects liver mitochondrial function and leads to neonatal lethality. Conditional homozygous KO in the adult liver affects cellular respiration under energy stress conditions. [provided by MGI curators] |