Primary Identifier | MGI:2661375 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 237847 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chondroitin sulfate binding activity and heparin binding activity. Involved in corpus callosum development and negative regulation of axon regeneration. Predicted to be located in cell surface and plasma membrane. Is expressed in brain; ganglia; heart; peripheral nervous system; and spinal cord. Orthologous to human RTN4RL1 (reticulon 4 receptor like 1). PHENOTYPE: Mice homozygous for disruptions in this gene display fatty change in the liver, bile duct lesions in females and hepatocytes with enlarged vacuoles and nuclei in the male. [provided by MGI curators] |