| Primary Identifier | MGI:106612 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 17913 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microfilament motor activity. Acts upstream of or within several processes, including cellular response to type II interferon; positive regulation of protein targeting to membrane; and vesicle transport along actin filament. Located in several cellular components, including brush border; cytoplasmic vesicle; and stereocilium. Is expressed in brain vascular element; cerebral cortex ventricular layer; cochlea; and cortical plate. Orthologous to human MYO1C (myosin IC). PHENOTYPE: Mice homozygous for a knock-in (Y61G) mutation that sensitizes to N6-modified ADP analogs display altered fast adaption in vestibular hair cells. Mice homozygous for a nuclear isoform-specifc knock-out allele exhibit minor changes in bone marrow density and red blood cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
