Primary Identifier | MGI:2444198 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 320522 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Is expressed in several structures, including central nervous system; foregut; genitourinary system; limb; and limb bud. Orthologous to human BHLHA9 (basic helix-loop-helix family member a9). PHENOTYPE: Mice homozygous for a null allele exhibit variable asymmetrical syndactyly and interdigital webbing due to reduced interdigital apoptosis and incomplete separation of soft, but not skeletal, tissues between forelimb digits 2 and 3. [provided by MGI curators] |