Primary Identifier | MGI:107726 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 20926 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone binding activity and nucleosome binding activity. Involved in several processes, including regulation of mRNA export from nucleus; regulation of nucleobase-containing compound metabolic process; and transcription elongation-coupled chromatin remodeling. Acts upstream of or within blastocyst formation. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including brain; early conceptus; genitourinary system; retina; and spleen. Orthologous to human SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality during pre-implantation development. [provided by MGI curators] |