Primary Identifier | MGI:101863 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 11676 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fructose-bisphosphate aldolase activity. Involved in gluconeogenesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C). PHENOTYPE: Mice homozygous for a knock-out allele show decreased plasma levels of total cholesterol and HDL cholesterol in both sexes and decreased plasma triglyceride levels in females. [provided by MGI curators] |