| Primary Identifier | MGI:109496 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 16859 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including carbohydrate binding activity; galactoside binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including regulation of cytokine production; regulation of defense response; and regulation of leukocyte activation. Located in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; hemolymphoid system; intestine; liver; and metanephros. Orthologous to several human genes including LGALS9 (galectin 9) and LGALS9B (galectin 9B). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to collagen-induced arthritis, increased T-helper 1 cells and decreased regulatory T cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
