| Primary Identifier | MGI:1926078 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 59040 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in several processes, including establishment of mitochondrion localization, microtubule-mediated; mitochondrial outer membrane permeabilization; and regulation of organelle transport along microtubule. Located in mitochondrion. Is expressed in brain and head. Used to study motor neuron disease. Orthologous to human RHOT1 (ras homolog family member T1). PHENOTYPE: Mice homozygous for a null allele die neonatally exhibiting cyanosis, respiratory failure, loss of brainstem cranial motor neurons, decreased cervical motor neuron number and phrenic nerve branching, and alterations in retrograde mitochondrial transport and run length in cortical axons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
