| Primary Identifier | MGI:99512 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 20306 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables CCR2 chemokine receptor binding activity. Predicted to be involved in several processes, including cellular response to ethanol; eosinophil chemotaxis; and positive regulation of natural killer cell chemotaxis. Located in extracellular space. Is expressed in several structures, including central nervous system; leg; lung; retina; and vertebral axis musculature. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CCL7 (C-C motif chemokine ligand 7). PHENOTYPE: Mice homozygous for a knock-out allele exhibit alterations in blood monocyte counts and in the monocytic response to thioglycollate-induced inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
