Primary Identifier | MGI:1914588 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 67338 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme binding activity; p53 binding activity; and ubiquitin protein ligase activity. Involved in regulation of fibroblast migration. Acts upstream of or within intracellular protein transport. Located in cytoplasmic vesicle. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; liver; and retina nuclear layer. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase). PHENOTYPE: Mice homozygous for an inactivating targeted mutation of this gene are born at the expected Mendelian frequency; they are viable and fertile and exhibit no apparent abnormal phenotype. [provided by MGI curators] |