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Protein Coding Gene : Rad51d RAD51 paralog D
Primary Identifier  MGI:1261809 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  19364
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable ATP-dependent DNA damage sensor activity; gamma-tubulin binding activity; and single-stranded DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Involved in telomere maintenance. Acts upstream of or within chromosome organization; interstrand cross-link repair; and regulation of cell cycle. Located in chromosome, telomeric region. Is expressed in several structures, including gonad; heart; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in hereditary breast ovarian cancer syndrome. Orthologous to human RAD51D (RAD51 paralog D).
PHENOTYPE: Mice homozygous for disruptions in this gene die as embryos before E11.5. [provided by MGI curators]
  • synonyms:
  • Rad51l3,
  • Rad51d,
  • RAD51-like 3 (S. cerevisiae),
  • R51H3,
  • recombination and repair damage, RAD51D homolog (S. cerevisiae),
  • RAD51 paralog D
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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