Primary Identifier | MGI:2445121 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 237886 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATP hydrolysis activity; tRNA binding activity; and zinc ion binding activity. Predicted to be involved in defense response to virus; rRNA catabolic process; and tRNA decay. Located in nucleus. Orthologous to several human genes including SLFN13 (schlafen family member 13). PHENOTYPE: Homozygous null mice show resistance to CGT-motif containing ssDNA-induced inflammation, acute hepatitis, and septic shock. [provided by MGI curators] |