| Primary Identifier | MGI:2672859 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 276950 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA endonuclease activity. Involved in rRNA catabolic process and tRNA decay. Predicted to be located in cytosol; nucleoplasm; and site of DNA damage. Orthologous to several human genes including SLFN13 (schlafen family member 13). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to experimental autoimmune encephalomyelitis (EAE) and reduced pro-inflammatory cytokine levels after EAE induction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
