Primary Identifier | MGI:1329005 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 20557 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA nuclease activity and ribosome binding activity. Acts upstream of or within negative regulation of cell population proliferation. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; liver; sensory organ; and skeleton. Orthologous to several human genes including SLFN12L (schlafen family member 12 like). PHENOTYPE: Mice homozygous for a null allele exhibit normal immune cell populations and MOG-induced experimental autoimmune encephalitis development. [provided by MGI curators] |