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Protein Coding Gene : Slfn14 schlafen 14
Primary Identifier  MGI:2684866 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  237890
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables RNA endonuclease activity and ribosome binding activity. Involved in mRNA catabolic process and rRNA catabolic process. Located in nucleus. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 20. Orthologous to human SLFN14 (schlafen family member 14).
PHENOTYPE: Mice homozygous for a K208N mutation do not survive to weaning. Heterozygotes show microcytic erythrocytosis, hemolytic anemia, splenomegaly and abnormal thrombus formation. [provided by MGI curators]
  • synonyms:
  • Gm20,
  • gene model 20, (NCBI),
  • Slfn14,
  • schlafen 14,
  • Slfn14-ps,
  • schlafen family member 14, pseudogene,
  • LOC237890
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2 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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Mouse features --> Functions (GO terms)

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Disease

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