Primary Identifier | MGI:2685575 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 276952 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein activity and GTP binding activity. Involved in positive regulation of peptide hormone secretion and regulation of systemic arterial blood pressure by atrial natriuretic peptide. Predicted to be located in plasma membrane. Is expressed in several structures, including brain; heart; myotome; neural tube; and retina. Orthologous to human RASL10B (RAS like family 10 member B). PHENOTYPE: Mice homozygous for a knock-out allele have smaller than normal large dense-core vesicles in atrial myocytes and exhibit impaired atrial natriuretic peptide secretion. [provided by MGI curators] |