Primary Identifier | MGI:2153062 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 118453 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Acts upstream of or within negative regulation of macrophage chemotaxis. Located in cytoplasm. Is expressed in several structures, including heart; hindlimb; lung; nervous system; and skin. Orthologous to human MMP28 (matrix metallopeptidase 28). PHENOTYPE: Null homozygote mice have enhanced chemotaxis of macrophages into the lung upon infection. [provided by MGI curators] |