| Primary Identifier | MGI:98261 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 20303 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chemokine receptor binding activity and identical protein binding activity. Acts upstream of or within cellular response to xenobiotic stimulus. Located in extracellular space. Is expressed in central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL4 (C-C motif chemokine ligand 4). PHENOTYPE: Homozygous null mice with induced diabetic kidney disease show improved renal function, decreased renal glomerulosclerosis and fibrosis, decreased renal inflammation and reduced blood sugar levels compared to controls. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
