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Protein Coding Gene : Dusp14 dual specificity phosphatase 14

Primary Identifier  MGI:1927168 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  56405
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable phosphoprotein phosphatase activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human DUSP14 (dual specificity phosphatase 14).
PHENOTYPE: Homozygous KO results in increased T cell activation, proliferation and differentiation. It also causes increased cardiac hypertrophy in response to aortic banding. [provided by MGI curators]
  • synonyms:
  • Dusp14,
  • DNA segment, Chr 11, ERATO Doi 395, expressed,
  • MKP-L,
  • 2310042C07Rik,
  • MGI:1917390,
  • RIKEN cDNA 1110014C10 gene,
  • Mkp6,
  • dual specificity phosphatase 14,
  • MGI:1915839,
  • MGI:1196441,
  • 1110014C10Rik,
  • D11Ertd395e,
  • RIKEN cDNA 2310042C07 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For