| Primary Identifier | MGI:2387356 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 217039 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of cell population proliferation; and negative regulation of peptidyl-tyrosine phosphorylation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; retina; and spleen. Orthologous to human GGNBP2 (gametogenetin binding protein 2). PHENOTYPE: Homozygotes for a gene trapped allele die throughout fetal growth and development showing pallor and altered placental labyrinth vasculature. Most homozygotes for a null allele die in utero; survivors show male infertility, impaired spermatogenesis, increased testis apoptosis and azoospermia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
