| Primary Identifier | MGI:2385848 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 192197 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including acetyltransferase activator activity; beta-tubulin binding activity; and histone acetyltransferase binding activity. Involved in cell-cell signaling; positive regulation of endothelial cell migration; and regulation of actin cytoskeleton organization. Located in cell leading edge; cell periphery; and cytoskeleton. Is expressed in several structures, including embryo mesenchyme; genitourinary system; heart; hemolymphoid system; and yolk sac. Human ortholog(s) of this gene implicated in Hengel-Maroofian-Schols syndrome. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor). PHENOTYPE: Mice homozygous for a knock-out allele or a conditional allele activated in endothelial cells exhibit embryonic lethality with abnormal development and cardiovascular patterning. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
